![]() If you have HER2-positive or triple-negative breast cancer, talk to your doctor about the most appropriate treatment for you. While this research does not change any treatment recommendations, it does provide a hopeful possibility for a future treatment. Many studies will be needed to learn if it would be safe and helpful for people. The potential side effects of melittin in humans is unknown. It is not clear whether melittin would work the same way or be safe for people. The major limitation is that these studies have only been done in laboratory models in cells and mice. The findings support the idea that honeybee venom and its main ingredient, melittin, could kill breast cancer cells in a dish or in mice. Small human safety trials are required before larger studies can determine whether melittin is helpful for treating cancer in people. However, whether the same approach might work in people is unknown.īefore safety studies in humans could begin, many studies in other animals are needed to show whether melittin has other side effects. This suggests that melittin may be useful in treating cancer. The chemotherapy drug docetaxel combined with melittin killed breast cancer in mice more than docetaxel alone. Researchers modified the melittin protein to increase its ability to target cancer cells. Honeybee venom and its major component melittin kill human cancer cells in culture dishes, including cells from triple-negative and HER2-positive breast cancers, more effectively than normal cells. This study is an example of early research on a promising drug, melittin, in cells in a lab dish or in mice that may (or may not) be useful in breast cancer treatment of people in the future. These early lab studies help researchers select drugs that hold the most promise for clinical use. Early research on a possible treatment for breast cancer.Įarly (basic) research on new drugs often begins with cancer cells in a dish or in animals before any studies are done in humans.
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